The Sanchez Cartel was a Latin-American organized criminal empire based in Isthmus City in the Republic of Isthmus. The gang was ruled by drugs baron Franz Sanchez and the primary players were his enforcers Dario, Braun and Perez, head of security Colonel Heller, accountant Truman-Lodge and televangelist Professor Joe Butcher.

The Cartel was destroyed from within in 1989 by James Bond avenging the maiming of his best friend Felix Leiter and the murder of his wife Della Leiter.

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